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Unprecedented Cu(I)-Catalyzed Microwave-Assisted Three-Component Coupling of a Ketone, an Alkyne, and a Primary Amine

  作者 PERESHIVKO OLGA P; PESHKOV VSEVOLOD A; VAN DER EYCKEN ERIK V  
  选自 期刊  Organic Letters;  卷期  2010年12-11;  页码  2638-2641  
  关联知识点  
 

[摘要]An efficient, microwave-assisted Cu(I)-catalyzed one-pot coupling of a ketone, an alkyne, and a primary amine (KA(2) coupling) is described, giving access to secondary propargylamines.

 
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