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[摘要]:Aldehydes undergo smooth cyclization with 4-(phenylthio)but-3-en-1-ol in the presence of BF(3)center dot OEt(2) in dichloromethane at room temperature to afford a novel class of 2,3-disubstitued tetrahydrofurans in good yields with all-cis-selectivity. This method is simple, selective, and convenient for the synthesis of tetrahydrofuran scaffolds in a single step. |
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