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A facile synthesis of cycloether systems bearing [2,4]-oxazole units.

  作者 Incerti, Marcelo;Fontana, Carolina;Scarone, Laura;Moyna, Guillermo;Manta, Eduardo;  
  选自 期刊  Heterocycles;  卷期  2008年75-6;  页码  1385-1396  
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[摘要]We present a concise and high-yielding route for the prepn. of novel five-, six-, and seven-membered cycloether systems bearing [2,4]-oxazoles units. The approach is based on intramol. electrophilic oxirane ring expansion strategies and b-hydroxyamide cyclodehydration-oxidn. reactions mediated by Deoxo-Fluor and BrCCl3/DBU.

 
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