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Design, synthesis and biological evaluation of new ionone derivatives as potential neuroprotective agents in cerebral ischemia

  作者 Srivastava, AK; Dohare, P; Ray, M; Panda, G  
  选自 期刊  European Journal of Medicinal Chemistry;  卷期  2010年45-5;  页码  1964-1971  
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[摘要]A new series of ionone derived allylic alcohols have been evaluated for anti-ischemic activity. Out of them, 121 and 13b decreased infarct volume to 23.98 +/- 4.7 mm(3) and 93.98 /- 24.8 mm(3) as compared to ischemic group. (C) 2010 Elsevier Masson SAS. All rights reserved.

 
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