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Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development

  作者 Fernandez-Miranda, G; Trakala, M; Martin, J; Escobar, B; Gonzalez, A; Ghyselinck, NB; Ortega, S; Canamero, M; de Castro, IP; Malumbres, M  
  选自 期刊  Development;  卷期  2011年138-13;  页码  2661-2672  
  关联知识点  
 

[摘要]Mitosis is controlled by multiple kinases that drive cell cycle progression and prevent chromosome mis-segregation. Aurora kinase B interacts with survivin, borealin and incenp to form the chromosomal passenger complex (CPC), which is involved in the regu

 
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