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The Autistic Neuron: Troubled Translation?

  作者 Kelleher, RJ; Bear, MF  
  选自 期刊  Cell;  卷期  2008年135-3;  页码  401-406  
  关联知识点  
 

[摘要]Autism is a complex genetic disorder, but single-gene disorders with a high prevalence of autism offer insight into its pathogenesis. Recent evidence suggests that some molecular defects in autism may interfere with the mechanisms of synaptic protein synthesis. We propose that aberrant synaptic protein synthesis may represent one possible pathway leading to autistic phenotypes, including cognitive impairment and savant abilities.

 
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