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Palladium-Catalyzed Trifluoromethylation of Aromatic C-H Bond Directed by an Acetamino Group

  作者 ZHANG LISHENG; CHEN KANG; CHEN GUIHUA; LI BIJIE; LUO SHUANG; GUO QINGYUN; WEI JIANGBO; SHI ZHANGJIE  
  选自 期刊  Organic Letters;  卷期  2013年15-1;  页码  10-13  
  关联知识点  
 

[摘要]The first palladium-catalyzed ortho-trifluoromethylation of the aromatic C-H bond directed by an acetamino group is reported. This method provides an efficient and green approach to synthesize the highly biological potential key structure of ortho-CF3 acetanilides and anilines.

 
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