Phosphane-Mediated Domino Synthesis of Tetrasubstituted Furans from Simple Terminal Activated Olefins

[摘要]：Convenient and highly efficient syntheses of tetrasubstituted furans with flexible substituent patterns from simple and readily available starting materials have been developed. Under very mild conditions, with the mediation of stoichiometric nBu3P, simple terminal activated olefins and acyl chlorides or anhydrides smoothly furnish tetrasubstituted furans in modest to excellent yields. This synthetic strategy features a flexible selection of substituent pattern and a C-acylation/O-acylation/C-acylation/intramolecular Wittig reaction multiple domino assembly sequence.

[全文传递流程]：

一般上传文献全文的时限在1个工作日内