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Chiral Pyrrolidine Sulfonamide Catalyzed Enantioselective Michael Addition of Cyclohexanones to Maleimides

  作者 WANG JIAN; ZHANG MANMAN; ZHANG SHIELI; XU ZIAN; LI HAO; YU XINHONG; WANG WEI  
  选自 期刊  SYNLETT;  卷期  2011年-4;  页码  473-476  
  关联知识点  
 

[摘要]An organocatalytic enantioselective conjugate addition of cyclohexanones to maleimides has been developed. The process catalyzed by a (S)-pyrrolidine sulfonamide affords synthetically and medicinally useful chiral succinimides under mild reaction conditions.

 
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