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Toward the Synthesis of Benzothiazolyl Fluoroaminosulfones

  作者 CALATA CHARLENE; PFUND EMMANUEL; LEQUEUX THIERRY  
  选自 期刊  Journal of Organic Chemistry;  卷期  2009年74-24;  页码  9399-9405  
  关联知识点  
 

[摘要]Due to the importance of allylamines in organic synthesis, the synthesis of reagents as potent precursors of aminofluoroolefins is reported from functionalized benzothiazolylsulfones. The key intermediate, a fluorovinyl sulfone, was prepared and functionalized by addition of aliphatic, aromatic amines and amino acid alkyl esters through an aza-Michael addition reaction.

 
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