|
[摘要]:New 3-trifluoroacetyl-4-quinolylamines (2), sulfides (3), and ethers (4) were synthesized in good to high yields by aromatic nucleophilic substitution reactions of N,N-dimethyl-3-trifluoroacetyl-4-quinolylamine (1), which was easily prepared by acylation of N,N-dimethyl-4-quinolylamine with 1-trifluoroacetyl-4-dimethylaminopyridinium trifluoroacetate, with amines, thiols, alcohols, and phenols. |
|