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Organic Reactions in Water: A Practical and Convenient Method for the N-Formylation of Amines in Water

  作者 KABOUDIN BABAK; KHODAMORADY MINOO  
  选自 期刊  SYNLETT;  卷期  2010年-19;  页码  2905-2907  
  关联知识点  
 

[摘要]A simple, efficient, scaleable process has been developed for the N-formylation amines in water. Treatment of amines with triethyl orthoformate in water at reflux under neutral conditions without any additives gives the corresponding N-formyl derivatives in good yields.

 
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