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Duboscic Acid: A Potent alpha-Glucosidase Inhibitor with an Unprecedented Triterpenoidal Carbon Skeleton from Duboscia macrocarpa

  作者 WAFO PASCAL; KAMDEM RAMSAY S T; ALI ZULFIQAR; ANJUM SHAZIA; KHAN SHAMSUN NAHAR; BEGUM AFSHAN; KROHN KARSTEN; ABEGAZ BERHANU M; NGADJUI BONAVENTURE T; CHOUDHARY MUHAMMAD IQBAL  
  选自 期刊  Organic Letters;  卷期  2010年12-24;  页码  5760-5763  
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[摘要]Duboscic acid (1), a triterpenoid with a unique carbon backbone, was isolated from Duboscia macrocarpa Bocq. It is the first member of a new class of triterpenoids, for which the name "dubosane" is proposed. Duboscic acid has a potent a-glucosidase inhibition, and its structure was unambiguously deduced by a single-crystal X-ray diffraction study.

 
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