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Preparation and some synthetic applications of 2-hydroxyethyl-substituted cyclopropylamines.

  作者 Joosten, Antoine;Vasse, Jean-Luc;Bertus, Philippe;Szymoniak, Jan;  
  选自 期刊  SYNLETT;  卷期  2008年-16;  页码  2455-2458  
  关联知识点  
 

[摘要]Primary cyclopropylamines bearing hydroxy side chains were obtained by Ti-mediated coupling of nitriles and homoallylic alcs. Their usefulness as synthetic intermediates was demonstrated by the prepn. of a constrained glutamic acid deriv. and pyrrolizidine analogs.

 
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