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Palladium-Catalyzed Oxidative Arylalkylation of Unactivated Alkenes: Dual C-H Bond Cleavage of Anilines and Acetonitrile

  作者 ZHANG HAO; CHEN PINHONG; LIU GUOSHENG  
  选自 期刊  SYNLETT;  卷期  2012年-19;  页码  2749-2752  
  关联知识点  
 

[摘要]A palladium-catalyzed oxidative arylalkylation of unactivated alkenes involving dual C-H bond cleavage of arene and acetonitrile was developed. This reaction was promoted by pyridine as a ligand, and the ratio of palladium to pyridine is vital for this transformation. A series of nitrile-containing indolines were efficiently provided in moderate to good yields.

 
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