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Regioselective Deacetylation and Glycosylation in the Synthesis of the Sialyl Lewis X Tetrasaccharide, a Key Component of the Recognition Site of PSGL-1

  作者 PUDELKO MACIEJ; KOWALCZYK DANUTA; KUNZ HORST  
  选自 期刊  SYNLETT;  卷期  2010年-20;  页码  3023-3026  
  关联知识点  
 

[摘要]A high-yielding regioselective deprotection of three out of five hydroxy groups of a Lewis X trisaccharide, which proceeds under very mild basic conditions, and a regio- and stereoselective sialylation reaction enable an efficient access to the sialyl Lewis X tetrasaccharide.

 
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