New Pyrrolo[2,1-a]phthalazine Derivatives by One-Pot Three-Component Synthesis

[摘要]：The synthesis of the pyrrolo[2,1-a] phthalazine derivatives was performed by an efficient one-pot three-component reaction starting from phthalazine, 2-bromoacetophenones and nonsymmetrical and symmetrical acetylenic dipolarophiles in 1,2-epoxybutane as both reaction medium and HBr scavenger. The structure of the compounds was assigned by IR and NMR spectroscopy.

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