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Design and In Situ Characterization of Lipid Containers with Enhanced Drug Retention

  作者 Wong, B; Boyer, C; Steinbeck, C; Peters, D; Schmidt, J; van Zanten, R; Chmelka, B; Zasadzinski, JA  
  选自 期刊  ADVANCED MATERIALS;  卷期  2011年23-20;  页码  2320-2320  
  关联知识点  
 

[摘要]Vesosome with distinct interior (green, orange) and exterior (blue) bilayer membranes. Drugs are encapsulated within the interior compartments and are protected from blood serum components by the exterior membrane. The outer membrane can be decorated with PEG lipids (red) to prevent aggregation in the blood as well as specific labels or targeting ligands.

 
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