Synthesis of Multisubstituted Enamides via Pd-Catalyzed Chloroallylation of Ynamides

[摘要]：An atom-economic approach to the regio- and stereoselective assembly of highly substituted enamides is described via the Pd-catalyzed chloroallylation of ynamides at room temperature, which offers a simple and practical alternative to the stereodefined multisubstituted enamides.

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