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[摘要]:Intramolecular oxygen transfer of nitrone- and sulfoxide-alkynes was achieved using a catalytic amount of Au(I) and a stoichiometric amount of iodine. The Au(I)-catalyzed cyclization of a nitrone-terminal alkyne afforded a cyclic iminoester, while cyclization of analogous nitrone-internal alkynes yielded aldehyde enones. The I(2)-mediated cyclization of nitrone-alkynes afforded iodinated gamma-lactams and the I(2)-mediated internal redox of the closely related sulfoxide alkynes gave diketones functionalized with a thoiether. |
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