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Synthesis of C-13-labeled and functionalized Hyaluronan derivatives for biophysical studies and surface modifications

  作者 RIGOL STEPHAN; XIA LIANG; GIANNIS ATHANASSIOS  
  选自 期刊  Bioorganic & Medicinal Chemistry;  卷期  2013年21-3;  页码  733-741  
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[摘要]A convergent synthesis of a tetrasaccharide partial sequence of C-13-labeled Hyaluronan is presented. This tetrasaccharide can be used for biophysical studies as well as for surface modifications. Furthermore, tetrasaccharide 7 can be employed for the synthesis of additionally labeled higher oligomers of Hyaluronan on the basis of the presented methodology. (C) 2012 Elsevier Ltd. All rights reserved.

 
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