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A Straightforward Synthesis of Pyrazolines and Pyrazoles: Palladium-Catalyzed Carbonylative Vinylation-Cyclocondensation Reactions of Aryl Halides

  作者 WU XIAOFENG; NEUMANN HELFRIED; BELLER MATTHIAS  
  选自 期刊  European Journal of Organic Chemistry;  卷期  2011年-25;  页码  4919-4924  
  关联知识点  
 

[摘要]A novel consecutive one-pot synthesis of pyrazolines and pyrazoles starting from simple aryl halides, styrenes, carbon monoxide, and hydrazines has been established. Palladium-catalyzed carbonylative vinylation of aryl halides gave the corresponding chalcones, which are trapped in situ by addition of hydrazines.

 
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