| |
[摘要]：In continuation of our work, we synthesized 2-(sulfamoylphenyl)-4'-amino-4-(4 ''-hydroxyphenyl)-thiazole (3a), which were reacted with various (aryl/hetroaryl) aldehyde to form 2-(sulfamoylphenyl)-4'-( iminoaryl/hetroaryl)-4-(4 ''-hydroxyphenyl)-thiazoles (4a-f). Glucosylation of compounds (4a-f) have been done by using acetobromoglucose as a glucosyl donor to afford 2-(sulfamoylphenyl)-4'-(iminoaryl/hetroaryl)-4-(2,3,4,6-tetra-O-acetyl-4 ''-O-beta-D-glucosidoxyphenyl)-thiazoles (5a-f), further on deacetylation to produce 2-(sulfamoylphenyl)-4'-(iminoaryl/hetroaryl)-4-(4 ''-O-beta-D-glucosidoxyphenyl)-thiazoles (6a-f). The compounds are confirmed by FTIR, (1)H-NMR, (13)C-NMR, and ES-Mass spectral analysis. |
|
