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Lin28b Reprograms Adult Bone Marrow Hematopoietic Progenitors to Mediate Fetal-Like Lymphopoiesis

  作者 Yuan, J; Nguyen, CK; Liu, XH; Kanellopoulou, C; Muljo, SA  
  选自 期刊  Science;  卷期  2012年335-6073;  页码  1195-1200  
  关联知识点  
 

[摘要]The immune system develops in waves during ontogeny; it is initially populated by cells generated from fetal hematopoietic stem cells (HSCs) and later by cells derived from adult HSCs. Remarkably, the genetic programs that control these two distinct stem

 
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