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Auto-tandem catalysis: synthesis of 4H-pyrido[1,2-a]pyrimidin-4-ones via copper-catalyzed aza-Michael addition-aerobic dehydrogenation-intramolecular amidation

  作者 YANG YAN; SHU WENMING; YU SHANGBO; NI FAN; GAO MENG; WU ANXIN  
  选自 期刊  Chemical Communications;  卷期  2013年49-17;  页码  1729-1731  
  关联知识点  
 

[摘要]A copper-catalyzed domino synthesis of 4H-pyrido[1,2-a]pyrimidin4-ones has been developed from 1,4-enediones and 2-aminoheterocycles with air as the oxidant.

 
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