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FKBP12 Is a Critical Regulator of the Heart Rhythm and the Cardiac Voltage-Gated Sodium Current in Mice

  作者 Maruyama, M; Li, BY; Chen, HY; Xu, XH; Song, LS; Guatimosim, S; Zhu, WQ; Yong, WD; Zhang, WJ; Bu, GX; Lin, SF; Fishbein, MC; Lederer, WJ; Schild, JH; Field, LJ; Rubart, M; Chen, PS; Shou, WN  
  选自 期刊  Circulation Research;  卷期  2011年108-9;  页码  1042-U38  
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[摘要]Rationale: FK506 binding protein (FKBP) 12 is a known cis-trans peptidyl prolyl isomerase and highly expressed in the heart. Its role in regulating postnatal cardiac function remains largely unknown. Methods and Results: We generated FKBP12 overexpressing

 
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