Evidence for Pleiotropic Effects of Phosphodiesterase-5 (PDE5) Inhibitors: Emerging Concepts in Cancer and Cardiovascular Medicine

[摘要]：A new study reports that the PDE5 inhibitor, sildenafil, enhances the chemotherapeutic efficacy of the anticancer drug, doxorubicin (DOX), in prostate and other cancer cell lines, while alleviating the commonly observed cardiotoxic effects of DOX in norma

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