[摘要]：An efficient and simple method for the synthesis of new 2-aryl-2-(2,3,4,5-tetrahydro-2,4-dioxo-1H-1,5-benzodiazepin-3-yl)acetamides (=a-aryl-2,3,4,5-tetrahydro-2,4-dioxo-1H-1,5-benzodiazepine-3-acetamides) by a five-component condensation reaction of benzene-1,2-diamine (1), Meldrum's acid (2), aldehydes 3, isocyanides 4, and H2O in CH2Cl2 at room temperature is reported (Table 1 and Scheme 2). These products were evaluated in vitro for their antibacterial activities (Table 2).
