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Fully automated synthesis and initial PET evaluation of [C-11]PBR28

  作者 Wang, M; Yoder, KK; Gao, MZ; Mock, BH; Xu, XM; Saykin, AJ; Hutchins, GD; Zheng, QH  
  选自 期刊  Bioorganic & Medicinal Chemistry Letters;  卷期  2009年19-19;  页码  5636-5639  
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[摘要]Fully automated synthesis and initial PET evaluation of a TSPO radioligand, [C-11]PBR28 (N-(2[C-11]methoxybenzyl)-N-(4-phenoxypyridin-3-yl)acetamide), are reported. These results facilitate the potential preclinical and clinical PET studies of [C-11]PBR28 in animals and humans. (C) 2009 Elsevier Ltd. All rights reserved.

 
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