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p45NF-E2 represses Gcm1 in trophoblast cells to regulate syncytium formation, placental vascularization and embryonic growth

  作者 Kashif, M; Hellwig, A; Kolleker, A; Shahzad, K; Wang, HJ; Lang, S; Wolter, J; Thati, M; Vinnikov, I; Bierhaus, A; Nawroth, PP; Isermann, B  
  选自 期刊  Development;  卷期  2011年138-11;  页码  2235-2247  
  关联知识点  
 

[摘要]Absence of the leucine zipper transcription factor p45NF-E2 results in thrombocytopenia, impaired placental vascularization and intrauterine growth restriction (IUGR) in mice. The mechanism underlying the p45NF-E2-dependent placental defect and IUGR remai

 
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