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Synthesis of 4-, 5- and 6-benzoylated 7-azaindoles.

  作者 Pillard, Christelle;Bassene, Carine Ekambome;Suzenet, Franck;Guillaumet, Gerald;  
  选自 期刊  Synthesis;  卷期  2008年-13;  页码  2049-2054  
  关联知识点  
 

[摘要]Efficient syntheses of 4-, 5- and 6-benzoyl-7-azaindoles are described. Two strategies were developed: first, formation of 4-lithio- and 5-lithio-7-azaindole and reaction with aldehydes and second organomagnesium addn. to 6-cyano-7-azaindole. Both methods should allow the introduction of a diverse range of acyl substituents.

 
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