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Mild and General Zinc-Alkoxide-Catalyzed Allylations of Ketones with Allyl Pinacol Boronates

  作者 FANDRICK KEITH R; FANDRICK DANIEL R; GAO JOE J; REEVES JONATHAN T; TAN ZHULIN; LI WENJIE; SONG JINHUA J; LU BRUCE; YEE NATHAN K; SENANAYAKE CHRIS H  
  选自 期刊  Organic Letters;  卷期  2010年12-17;  页码  3748-3751  
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[摘要]A general and efficient zinc-alkoxide-catalyzed allylation of a diverse array of ketones with allyl boronates is presented. The methodology is effective with 2 mol % of catalyst and with relatively short reaction times. Studies of the key exchange process are presented, which support a cyclic transition state for the boron to zinc exchange.

 
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