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Cycloaddition chemistry of allenamides

  作者 Standen, PE; Kimber, MC  
  选自 期刊  Current Opinion in Drug Discovery & Development;  卷期  2010年13-6;  页码  645-657  
  关联知识点  
 

[摘要]Allenamides are electron-deficient equivalents of allenamines, which can participate in a range of cycloaddition reactions giving rise to novel heterocycles and diverse molecular architectures similar to those contained in natural products. This review summarizes some of the research conducted in this field, with particular reference to predicting the stereochemical outcomes of such transformations. The applications of allenamides in cycloaddition transformations are highlighted, providing insight into the potential utility of this under-used synthon.

 
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