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Induced stem cell neoplasia in a cnidarian by ectopic expression of a POU domain transcription factor

  作者 Millane, RC; Kanska, J; Duffy, DJ; Seoighe, C; Cunningham, S; Plickert, G; Frank, U  
  选自 期刊  Development;  卷期  2011年138-12;  页码  2429-2439  
  关联知识点  
 

[摘要]The evolutionary origin of stem cell pluripotency is an unresolved question. In mammals, pluripotency is limited to early embryos and is induced and maintained by a small number of key transcription factors, of which the POU domain protein Oct4 is conside

 
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