Synthesis of Novel Spiro Thiazolotriazole Derivatives via 1,3-Dipolar Cycloaddition of Azomethine Ylide

[摘要]：The 1,3-dipolar cycloaddition of azomethine ylide generated in situ from isatin and sarcosine to 5-arylmethylidene thiazolo[3,2-b][1,2,4]triazol-6(5H)-ones afforded novel 1'-methyl-4'-aryldispiro [indole-3,2'-pyrrolidine-3',5 ''-[1,3]thiazolo[3,2-b][1,2,4]triazole]-2,6 '' (H-1)-diones in moderate yields. The structures of all the products were characterized thoroughly by NMR, infrared spectroscopy (IR), mass spectroscopy (MS) elemental analysis together with X-ray crystallographic analysis.

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