[摘要]：A series of 3'-methyl-branched and purine-modified analogs of aristeromycin were synthesized via the SN2 displacement of a key triflate, which was prepd. from a readily available enantiopure building block in eight steps. The synthesized compds. were evaluated as potential antiviral agents against important viruses. Only the 2,6-diaminopurine deriv. exhibited moderate activity against vesicular stomatitis virus.
