个性化文献订阅>期刊> Current Pharmaceutical Design
 

Transgenic Mouse Models of Alzheimer Disease: Developing a Better Model as a Tool for Therapeutic Interventions

  作者 Kitazawa, M; Medeiros, R; LaFerla, FM  
  选自 期刊  Current Pharmaceutical Design;  卷期  2012年18-8;  页码  1131-1147  
  关联知识点  
 

[摘要]Alzheimer disease (AD) is the leading cause of dementia among elderly. Currently, no effective treatment is available for AD. Analysis of transgenic mouse models of AD has facilitated our understanding of disease mechanisms and provided valuable tools for evaluating potential therapeutic strategies. In this review, we will discuss the strengths and weaknesses of current mouse models of AD and the contribution towards understanding the pathological mechanisms and developing effective therapies.

 
      被申请数(0)  
 

[全文传递流程]

一般上传文献全文的时限在1个工作日内