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Copper-Mediated Oxidative Cross-Coupling Reaction of Terminal Alkynes with alpha-Silyldifluoromethylphosphonates: An Efficient Method for alpha,alpha-Difluoropropargylphosphonates

  作者 JIANG XUELIANG; CHU LINGLING; QING FENGLING  
  选自 期刊  Organic Letters;  卷期  2012年14-11;  页码  2870-2873  
  关联知识点  
 

[摘要]A copper-mediated oxidative cross-coupling reaction of terminal alkynes with readily available alpha-silyldifluoromethylphosphonates under mild conditions has been developed. This method allows for an efficient synthesis of a series of synthetically useful alpha,alpha-difluoropropargylphosphonates with excellent functional group compatibility.

 
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