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Organosilicon Molecules with Medicinal Applications

  作者 FRANZ ANNALIESE K; WILSON SEAN O  
  选自 期刊  Journal of Medicinal Chemistry;  卷期  2013年56-2;  页码  388-405  
  关联知识点  
 

[摘要]The incorporation of silicon and synthesis of organosilicon small molecules provide unique opportunities for medicinal applications. The biological investigation of organosilicon small molecules is particularly interesting because of differences in their chemical properties that can contribute to enhanced potency and improved pharmacological attributes. Applications such as inhibitor design, imaging, drug release technology, and mapping inhibitor binding are discussed.

 
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