Palladium-Catalyzed Intermolecular Domino Reaction of gem-Dibromoenynes with Anilines; A One-Pot Synthesis of Quinolines and Quinolinones

[摘要]：An efficient domino process involving palladium-catalyzed amination of an alkenyl bromide, 1,5-H transfer, annulation via 6-exo-dig electrophilic cyclization, and palladium-catalyzed etherification, is described. This reaction provides an efficient one-pot synthesis of multi-substituted quinolines and quinolinones from gem-dibromoenynes and anilines.

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