Synthesis and biological evaluation of benzo[d]imidazole derivatives as potential anti-cancer agents

[摘要]：We herein report the synthesis, biological activity and structure-activity relationship of derivatives of 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole and benzo[d]imidazole. A lead compound 6o demonstrates potent anti-proliferative activity and the ability to induce cancer cell apoptosis. (C) 2011 Elsevier Ltd. All rights reserved.

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