A General Regioselective Synthesis of 2,4-Diarylpyrimidines from 2-Thiouracil through Two Orthogonal Cross-Coupling Reactions

[摘要]：A novel efficient synthesis of 2,4-diarylpyrimidines was developed based on phosphonium-mediated Suzuki coupling of 2-(methylsulfanyl) pyrimidin-4(3H)-one (at position 4) followed by the Liebeskind-Srogl cross-coupling (at position 2) under microwave irradiation.

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