SYNTHESIS OF A LIBRARY OF 1,5,2-DITHIAZEPINE 1,1-DIOXIDES. PART 2: ROUTES TO BICYCLIC SULTAMS

[摘要]：The synthesis of a library of bicyclic sultams incorporating the 1,5,2-dithiazepine 1,1-dioxide moiety is reported. Following scaffold synthesis via a one-pot sulfonylation/intramolecular thia-Michael protocol, several additional cyclization strategies have been realized enabling access to new bicyclic sultams.

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