CuI/SnCl2 Co-Catalyzed Four-Component Reaction of Ketones, Amines, Alkynes, and Carbon Dioxide

[摘要]：The four-component CuI and SnCl2 co-catalyzed assembly of ketones, amines, alkynes, and carbon dioxide could be performed in DMSO at 70 degrees C under CO2 pressure to synthesize 5-alkynlene oxazolidinones. It was found that steric hindrance had an extreme effect on the four-component coupling. Aliphatic ketones, basic primary amines, and aryl alkynes were good substrates.

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