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Synthesis of Norcantharidin-dimer Derivatives

  作者 DENG LIPING; YONG ZHANG; TAO WEIFENG; SHEN JIANFENG; WANG WEI  
  选自 期刊  Journal of Heterocyclic Chemistry;  卷期  2011年48-1;  页码  158-161  
  关联知识点  
 

[摘要]We use one molecule of ethylene diamine as a connecting arm to combine two molecules of 5,6-dehydronorcantharidin. Then, ten novel norcantharidin derivatives were synthesized in a single step by the [3 + 2] 1,3-dipolar cycloaddition reaction with oxime or hydrazone in the presence of chloramine-T, which is simpler than the conventional method.

 
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