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Rat brains also have a default mode network

  作者 Lu, HB; Zou, QH; Gu, H; Raichle, ME; Stein, EA; Yang, YH  
  选自 期刊  Proceedings of the National Academy of Sciences of the United States of America;  卷期  2012年109-10;  页码  3979-3984  
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[摘要]The default mode network (DMN) in humans has been suggested to support a variety of cognitive functions and has been implicated in an array of neuropsychological disorders. However, its function (s) remains poorly understood. We show that rats possess a DMN that is broadly similar to the DMNs of nonhuman primates and humans. Our data suggest that, despite the distinct evolutionary paths between rodent and primate brain, a well-organized, intrinsically coherent DMN appears to be a fundamental feature in the mammalian brain whose primary functions might be to integrate multimodal sensory and affective information to guide behavior in anticipation of changing environmental contingencies.

 
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