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Microwave-Assisted Click Chemistry Synthesis of 1,2,3-Triazoles from Aryldiazonium Silica Sulfates in Water

  作者 ZAREI AMIN; KHAZDOOZ LEILA; HAJIPOUR ABDOL R; AGHAEI HAMIDREZA; AZIZI GHOBAD  
  选自 期刊  Synthesis;  卷期  2012年44-21;  页码  3353-3360  
  关联知识点  
 

[摘要]A microwave-assisted click chemistry synthesis of 1,4-disubstituted 1,2,3-triazoles is studied by in situ generation of aryl azides via the reaction of aryldiazonium silica sulfates and sodium azide, followed by coupling with a terminal alkyne in the presence of copper catalyst. These reactions are carried out in water under mild and heterogeneous conditions without using any additional ligands.

 
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