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Synthesis and Use of a Trifluoromethylated Azomethine Ylide Precursor

  作者 GAEL TRAN; MEIER ROBIN; HARRIS LAWRENCE; BROWNE DUNCAN L; LEY STEVEN V  
  选自 期刊  Journal of Organic Chemistry;  卷期  2012年77-24;  页码  11071-11078  
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[摘要]The presence of fluorous substituents can impart a dramatic effect on the efficacy of molecules used for a range of applications in society. Here, we describe the preparation and use of a new trifluoromethylated azomethine ylide precursor, which leads to a series of fluorinated pyrrolidine, 3-pyrroline, and pyrrole building blocks.

 
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