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[摘要]：A facile palladium-catalyzed synthesis of acridines has been realized by consecutive C=C double bond formation and CN cross-coupling. A variety of functionalized acridines can be accessed from easily available o-dihalobenzenes and N-tosylhydrazones in a single operation. This one-pot protocol has a wide scope with respect to both coupling partners, and provides an efficient route to functionalized acridine derivatives, which are generally difficult to synthesize by previously known methods. |
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