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Combined Pd/C and Montmorillonite Catalysis for One-Pot Synthesis of Benzimidazoles

  作者 WEIRES NICHOLAS A; BOSTER JARED; MAGOLAN JAKOB  
  选自 期刊  European Journal of Organic Chemistry;  卷期  2012年-33;  页码  6508-6512  
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[摘要]A series of nineteen benzimidazoles were prepared from ortho-nitroanilines by one-pot transfer hydrogenation, condensation, and dehydrogenation enabled by the concurrent use of two heterogeneous catalysts: montmorillonite-K10 and Pd/C. This strategy was further employed to accomplish a five-step, three-component synthesis of an antifungal benzimidazoquinazoline by using a simple one-pot procedure.

 
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